Sanofi and Rigneydolphin have both confirmed to WLR that they are responding to a single positive coronavirus case each.
While there has been a reported case of Covid-19 at toy-maker Cartamundi.
Both of the individuals at Sanofi and Rigneydolphin are currently self-isolating at home.
It's understood that the Sanofi employee picked up the virus through community transmission, while Rigneydolphin believe their member of staff has had limited close contacts within their office.
In separate statements, both companies say they have implemented work from home policies since March and have taken significant steps to ensure social distancing and sanitation measures.
When contacted by WLR, Cartamundi declined to comment.