Liam Cahill's Waterford side will kickstart their Allianz National Hurling League Division 1B campaign away to Dublin in Parnell Park on February 6th.
The Deise will also face the long trip to Antrim as well as a visit to their near-neighbours Kilkenny as part of their 2022 campaign.
Laois and Tipperary will be this year's visitors to Walsh Park.
Last season, Cahill's men defeated both counties on their way to the All-Ireland semi-final, where they defeated by eventual Liam McCarthy winners, Limerick.
The campaign will begin in Parnell Park on February 6th, before entertaining Laois at home a week later.
February 27th will see the Deise head North to Corrigan Park, Belfast for a 1pm throw-in.
March 6th is a day to mark in the calendar as Cahill goes toe-to-toe with his home-county, looking for a third win on the spin against the Premier in all competitions.
St. Patrick's Weekend will throw up a storm on March 20th as the Deise will finish Group 1B with a trip to Nowlan Park to face arch-rivals Kilkenny.
Football
Ephie Fitzgerald's first Division 4 game as Waterford football boss will be at home to Tipperary in Fraher Field on January 30th.
They also make the trip to London to McGovern Park on February 6th.
There's then a weekend off before staying in the South-East when making the trip to Carlow on February 19th.
Leitrim will make their way to Dungarvan for February 27th, before also keeping it local by heading to Wexford on March 13th.
Sligo at home is on the agenda on March 20th before the campaign finishes with a trip to Breffni Park to face Cavan on the 27th.