Rob Kearney has emerged as Ireland's latest doubt for Sunday's World Cup opener with Scotland.
The Leinster full-back is understood to have suffered a calf injury in training today in Chiba.
Robbie Henshaw is also likely to miss the game with a hamstring problem.
However, Joey Carbery is expected to feature against the Scots.
The Munster outhalf has returned to full training, after missing three of the four pre-season games due to an ankle injury.