Test starts for Hugo Keenan and Will Connors resulted in a wide score line victory for Andy Farrell in his fourth game in charge.
Ireland top the table as they head to Paris for the final game of the tournament - but the advantage is likely in the hands of England.
The French side is rejuvenated compared to recent years with issues of unreliability less than what they once were.
England have the opportunity to round out their campaign with a rout over Italy similar to that or Ireland today - a bonus point is all but certain for Eddie Jones' men.
Andy Farrell will need to ensure his team can come away with a bonus point victory over the French to preserve their hopes of lifting the trophy.
In todays game, new fewer than six try scorers crossed the white wash - with Johnny Sexton (captain), CJ Stander, Hugo Keenan, Bunee Aki, Ed Byrne and Will Connors all registering on the score sheet.
Sexton notched all but one of his kicks which will be something the French team need to consider ahead of the meeting, knowing that soft penalties will carry a heavy cost.
