David McCord is serving a life sentence after he was convicted of murder in 2003.
He was in the custody of prison staff at a property in the Crumlin Road area of Belfast last Friday.
He was last seen on the Castlereagh Road at around 4:30 that afternoon - and was wearing a green jacket, and black tracksuit bottoms and was carrying a red carrier bag.
The PSNI is appealing to anyone who has seen Mr McCord to contact them, while they are also appealing directly to him to hand himself in.
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